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Product Name MPP2 Chinese Name MPP2蛋白抗体 Alias D11BWG0652E; Discs Large Homolog 2; DLG2; DLGH2; Homolog of DLG A tumor supressor; MAGUK p55 Subfamily Member 2; Membrane Protein Palmitoylated 2; MPP2_HUMAN; PALS4. Research Area Tumour Cell biology Signal transduction The cell membrane蛋白 Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 62 kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MPP2: 351-450/576 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail MPP2 (Palmitoylated membrane protein 2) is a member of a family of membrane associated proteins termed MAGUKs (membrane associated guanylate kinase homologs). These proteins interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. MPP2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction.
Subcellular Location:
Cell Membrane; integral membrane protein
Similarity:
Belongs to the MAGUK family.
Contains 1 guanylate kinase-like domain.
Contains 2 L27 domains.
Contains 1 PDZ (DHR) domain.
Contains 1 SH3 domain.
SWISS:
Q14168
Gene ID:
4355
Database links:Entrez Gene: 4355 Human
Entrez Gene: 50997 Mouse
Omim: 600723 Human
SwissProt: Q14168 Human
SwissProt: Q9WV34 Mouse
Unigene: 514208 Human
Unigene: 36242 Mouse
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