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Product Name FA20A Chinese Name FA20A抗体 Alias FA20A_HUMAN; Protein FAM20A. Research Area Cell biology Stem cells Cell differentiation Immunogen Species Rabbit Clonality Polyclonal React Species Human, Mouse, (predicted: Rat, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 57kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FA20A: 101-200/541 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail FA20A belongs to the FAM20 family. All FAM20 proteins contain putative conserved signal sequences as well as a conserved C terminal domain. FA20A is a secreted glycoprotein. It has been found in EML and MPRO cell lines, with low levels in undifferentiated cells. FA20A is induced during maturation to promyelocyte stage of neutrophil differentiation and decreased during neutrophil terminal differentiation.
Subcellular Location:
Secreted
Tissue Specificity:
Highly expressed in lung and liver. Intermediate levels in thymus and ovary.
Post-translational modifications:
N-glycosylated (By similarity).
DISEASE:
Amelogenesis imperfecta and gingival fibromatosis syndrome (AIGFS) [MIM:614253]: An autosomal recessive condition characterized by mild gingival fibromatosis and dental anomalies, including hypoplastic amelogenesis imperfecta, intrapulpal calcifications, delay of tooth eruption, hypodontia/oligodontia, pericoronal radiolucencies, and unerupted teeth. Note=The disease is caused by mutations affecting the gene represented in this entry.
Similarity:
Belongs to the FAM20 family.
SWISS:
Q96MK3
Gene ID:
54757
Database links:Entrez Gene: 54757 Human
Omim: 611062 Human
SwissProt: Q96MK3 Human
Unigene: 268874 Human
Product Picture Sample: Lung(Mouse) Lysate at 40 ug
Primary: Anti-FA20A(SL10196R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 57 kD
Observed band size: 57 kD
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