Product Name	HCG3
Chinese Name	HCG3蛋白抗体
Alias	DnaJ (Hsp40) homolog subfamily B member 3; DnaJ homolog subfamily B member 3; Dnajb3; DNJB3_HUMAN; HCG3 gene; HCG3 protein; Hypothetical protein LOC414061; MGC26879; Putative uncharacterized protein tmp_locus_21; Tmp_locus_21.
Research Area	Cell biology  Developmental biology  Signal transduction  Stem cells
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Pig, Cow, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	17kDa
Cellular localization	Extracellular matrix
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human HCG3: 1-100/145
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. Members of the DnaJ family are characterized by the presence of the J domain. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. Proteins of the DnaJ family contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. Function: May operate as a co-chaperone of the male germ cell- and haploid stage-specific Hsp70 proteins. Tissue Specificity: Expressed in sperm (at protein level). Similarity: Contains 1 J domain. SWISS: Q8WWF6 Gene ID: 414061 Database links: Entrez Gene: 414061 Human SwissProt: Q8WWF6 Human Unigene: 725533 Human
Product Picture	Sample: testis (Mouse) Lysate at 40 ug Primary: Anti-HCG3(SL13610R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 17 kD Observed band size: 19 kD

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