Product Name	ZNF206
Chinese Name	Zinc finger protein206抗体
Alias	Zfp206; Zinc finger and SCAN domain-containing protein 10; Zinc Finger Protein 206; ZSCAN10; ZSC10_HUMAN.
Research Area	Cell biology  Neurobiology  Stem cells  transcriptional regulatory factor  Zinc finger protein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Horse, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	80kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ZNF206: 551-650/725
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF206 (zinc finger protein 206), also known as ZSCAN10 (zinc finger and SCAN domain containing 10), is a 725 amino acid protein that contains one SCAN box domain and 14 C2H2-type zinc fingers. Localized to the nucleus, ZNF206 is thought to play a role in transcriptional regulation events. The gene encoding ZNF206 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. Function: Znf206 is a zinc finger protein and probable transcriptional regulator. It is expressed in embryonic stem cells and downregulated upon differentiation. Both Oct4 and Sox2 bind the znf206 gene. Subunit: Interacts with POU5F1/OCT4 and SOX2 (By similarity). Subcellular Location: Nuclear Similarity: Contains 14 C2H2-type zinc fingers. Contains 1 SCAN box domain. SWISS: Q96SZ4 Gene ID: 84891 Database links: Entrez Gene: 84891 Human Entrez Gene: 332221 Mouse SwissProt: Q96SZ4 Human SwissProt: Q20D61 Mouse Unigene: 334515 Human Unigene: 270315 Mouse

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