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Product Name JHDM1 Chinese Name JmjC结构域组蛋白去甲基化酶H3-K36抗体 Alias JHD1; JHD1; Jhd1p; JmjC domain containing histone demethylation protein 1; JmjC domain-containing histone demethylation protein 1; Jumonji/ARID domain containing protein 1; ScJHDM1; JHD1_YEAST. Immunogen Species Rabbit Clonality Polyclonal Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 57kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from YEAST of JHDM1: 101-200/492 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail KDM2 / JHD1 is a JmjC domain family histone demethylase specific for H3-K36, similar to proteins found in human, mouse, drosophila, X. laevis, C. elegans, and S. pombe.
Function:
Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Does not demethylate H3 'Lys-4' nor 'Lys-79'. {ECO:0000269|PubMed:16362057}.
Subcellular Location:
Nuclear.
Similarity:
Belongs to the JHDM1 histone demethylase family.
SWISS:
P40034
Gene ID:
856777
Database links:Entrez Gene: 856777 Saccharomyces cerevisiae
SwissProt: P40034 Saccharomyces cerevisiae
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