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Rabbit Anti-ZNF575 antibody
Rabbit Anti-ZNF575 antibody
Zinc finger protein 575; ZN575_HUMAN; Znf575.
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  • NO.:SL13588R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Rat,(predicted: Human,Mouse,Dog,Pig,Cow,Horse,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
  • Goods click count:20
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Details

Product Name ZNF575
Chinese Name Zinc finger protein575抗体
Alias Zinc finger protein 575; ZN575_HUMAN; Znf575.  
literatures
Specific References  (1)     |     SL13588R has been referenced in 1 publications.
[IF=4.938] NING AN. et al. The zinc figure protein ZNF575 impairs colorectal cancer growth via promoting p53 transcription. ONCOL RES. 2023; 31(3): 307–316  IHC ;  Human,Mouse.  
Research Area Cell biology  immunology  Chromatin and nuclear signals  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 27kDa
Cellular localization The nucleus 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human ZNF575: 51-150/245 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 575 (ZNF575) is a 245 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZNF575 contains six C2H2-type zinc fingers through which it is thought to be involved in DNA-binding and transcriptional regulation.

Function:
May be involved in transcriptional regulation.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 6 C2H2-type zinc fingers.

SWISS:
Q86XF7

Gene ID:
284346

Database links:

Entrez Gene: 284346 Human

Entrez Gene: 101544 Mouse

Entrez Gene: 308430 Rat

SwissProt: Q86XF7 Human

SwissProt: Q3TXZ1 Mouse

Unigene: 213534 Human

Unigene: 20117 Mouse



Product Picture
Paraformaldehyde-fixed, paraffin embedded (rat testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ZNF575) Polyclonal Antibody, Unconjugated (SL13588R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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