Product Name	ZBTB7C
Chinese Name	Zinc finger proteinZBTB7C抗体
Alias	APM 1; APM1; B230208J24Rik; FLJ37907; ZBTB36; Zinc finger and BTB domain containing 7C.
literatures	Specific References  (1)     |     SL13583R has been referenced in 1 publications. [IF=3.375] Xuenuo Chen. et al. Zinc finger and BTB domain-containing 7C (ZBTB7C) expression as an independent prognostic factor for colorectal cancer and its relevant molecular mechanisms. Am J Transl Res. 2020; 12(8): 4141–4159  IHC ;  Human.   PubMed:32913494
Research Area	transcriptional regulatory factor  Zinc finger protein  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Chicken, Pig, Cow, Horse, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	69kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ZBTB7C: 351-450/619
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. The Zinc finger and BTB domain-containing protein 7C (ZBTB7C), also designated affected by papillomavirus DNA integration in ME180 cells protein 1 (APM-1), contains 1 BTB (POZ) domain and 4 C2H2-type zinc fingers. ZBTB7C is detected in normal cervical keratinocytes and may be a potential tumor suppressor gene against human papillomavirus (HPV) mediated cervical carcinogenesis. Function: The function of Anti-ZBTB7C has not yet been determined. Tissue Specificity: Detected in normal cervical keratinocytes, and in some cervical carcinoma cell lines. Similarity: Contains 1 BTB (POZ) domain. Contains 4 C2H2-type zinc fingers. SWISS: A1YPR0 Gene ID: 201501 Database links: Entrez Gene: 201501 Human Entrez Gene: 207259 Mouse SwissProt: A1YPR0 Human SwissProt: Q8VCZ7 Mouse Unigene: 515388 Human
Product Picture	Sample: A549 (human)Cell Lysate at 40 ug Primary: Anti-ZBTB7C(SL13583R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 69 kD Observed band size: 63 kD

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