TEL: +86 571 56623320 EMAIL: [email protected]
Product Name ZADH1 Chinese Name 锌结合乙醇脱氢酶结构域蛋白1抗体 Alias 15 oxoprostaglandin 13 reductase; 15 oxoprostaglandin delta 13 reductase; 15-oxoprostaglandin 13-reductase; DKFZp686P10120; FLJ39091; FLJ99229; PGR 2; PGR2; PRG-2; Prostaglandin reductase 2; PTGR 2; PTGR2; PTGR2_HUMAN; Zinc binding alcohol dehydrogenase domain containing 1; Zinc binding alcohol dehydrogenase domain containing protein 1; Zinc-binding alcohol dehydrogenase domain-containing protein 1. Research Area Cell biology immunology Signal transduction The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 38kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ZADH1: 251-351/351 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.
Function:
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation (By similarity).
Subunit:
Monomer
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Widely expressed.
Similarity:
Belongs to the NADP-dependent oxidoreductase L4BD family.
SWISS:
Q8N8N7
Gene ID:
145482
Database links:Entrez Gene: 145482 Human
GenBank: NP_001139626.1 Human
Omim: 608642 Human
SwissProt: Q8N8N7 Human
Unigene: 632344 Human
Scan Wechat Qrcode