Product Name	ZNF93
Chinese Name	Zinc finger protein93抗体
Alias	FLJ12488; HPF34; HTF34; TF34; Zinc finger protein 505; Zinc finger protein 93 (HTF34); Zinc finger protein 93; Zinc finger protein HTF34; ZNF505; ZNF93; ZNF93_HUMAN.
literatures	Specific References  (1)     |     SL13558R has been referenced in 1 publications. [IF=0.252] Xiao-Xiao Cui. et al. High expression of ZNF93 promotes proliferation and migration of ovarian cancer cells and relates to poor prognosis. Int J Clin Exp Patho. 2020; 13(5): 944–953  IHC ;  Human.   PubMed:32509065
Research Area	Cell biology  Signal transduction  transcriptional regulatory factor  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	71kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ZBT24/ZNF45: 521-620/620
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Transcription factor specifically required to repress long interspersed nuclear element 1 (L1) retrotransposons: recognizes and binds L1 sequences and repress their expression by recruiting a repressive complex containing TRIM28/KAP1 (PubMed:25274305). Not able to repress expression of all subtypes of L1 elements. Binds to the 5 end of L1PA4, L1PA5 and L1PA6 subtypes, and some L1PA3 subtypes. Does not bind to L1PA7 or older subtypes nor at the most recently evolved L1PA2 and L1Hs. 50% of L1PA3 elements have lost the ZNF93-binding site, explaining why ZNF93 is not able to repress their expression (PubMed:25274305). Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus. DISEASE: Expressed early during embryonic development. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 17 C2H2-type zinc fingers. Contains 1 KRAB domain. SWISS: P35789 Gene ID: 81931 Database links: Entrez Gene: 81931 Human Omim: 603975 Human SwissProt: P35789 Human Unigene: 301059 Human Unigene: 723768 Human
Product Picture	Sample: HL-60 (human)cell Lysate at 40 ug MCF-7 (human)cell Lysate at 40 ug Primary: Anti-ZNF93 (SL13558R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 71 kD Observed band size: 71 kD

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