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Rabbit Anti-GNPNAT1 antibody
Rabbit Anti-GNPNAT1 antibody
AU017428; AU040593; EMeg32; FLJ10607; Glucosamine 6 phosphate acetyltransferase; Glucosamine 6 phosphate N acetyltransferase; Glucosamine 6-phosphate N-acetyltransferase; Glucosamine phosphate N acetyltransferase 1; GNA1; GNA1_HUMAN; GNPNAT; GNPNAT1; Gpna
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  • NO.:SL13475R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Pig,Cow,Rabbit,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name GNPNAT1
Chinese Name 葡萄糖6-N-乙酰基转移酶1抗体
Alias AU017428; AU040593; EMeg32; FLJ10607; Glucosamine 6 phosphate acetyltransferase; Glucosamine 6 phosphate N acetyltransferase; Glucosamine 6-phosphate N-acetyltransferase; Glucosamine phosphate N acetyltransferase 1; GNA1; GNA1_HUMAN; GNPNAT; GNPNAT1; Gpnat1; Gsnpat; Phosphoglucosamine acetylase; Phosphoglucosamine transacetylase; RGD1563144.  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Pig, Cow, Rabbit, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 21kDa
Cellular localization cytoplasmic The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human GNPNAT1/GNA1: 101-184/184 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Glucosamine 6-phosphate N-acetyltransferase (GNA1), also designated phosphoglucosamine transacetylase or phosphoglucosamine acetylase, belongs to the GNA1 subfamily of the larger acetyltransferase family of proteins. GNA1, a peripheral membrane protein containing one N-acetyltransferase domain, is expressed in the colon and maps to cytoband 14q22.1. The protein localizes to the Golgi apparatus and the endosome. It is important for UDP-GlcNAc biosynthesis pathway. GNA1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.

Function:
Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 1/2.

Subcellular Location:
Golgi apparatus membrane. Endosome membrane.

Similarity:
Belongs to the acetyltransferase family.
GNA1 subfamily.
Contains 1 N-acetyltransferase domain.

SWISS:
Q96EK6

Gene ID:
64841

Database links:

Entrez Gene: 64841 Human

Entrez Gene: 54342 Mouse

Entrez Gene: 498486 Rat

Entrez Gene: 512299 Cow

SwissProt: Q96EK6 Human

SwissProt: Q9JK38 Mouse

Unigene: 702056 Human

Unigene: 312945 Mouse

Unigene: 14702 Rat



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