TEL: +86 571 56623320 EMAIL: [email protected]
Product Name GNPNAT1 Chinese Name 葡萄糖6-N-乙酰基转移酶1抗体 Alias AU017428; AU040593; EMeg32; FLJ10607; Glucosamine 6 phosphate acetyltransferase; Glucosamine 6 phosphate N acetyltransferase; Glucosamine 6-phosphate N-acetyltransferase; Glucosamine phosphate N acetyltransferase 1; GNA1; GNA1_HUMAN; GNPNAT; GNPNAT1; Gpnat1; Gsnpat; Phosphoglucosamine acetylase; Phosphoglucosamine transacetylase; RGD1563144. Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 21kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GNPNAT1/GNA1: 101-184/184 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Glucosamine 6-phosphate N-acetyltransferase (GNA1), also designated phosphoglucosamine transacetylase or phosphoglucosamine acetylase, belongs to the GNA1 subfamily of the larger acetyltransferase family of proteins. GNA1, a peripheral membrane protein containing one N-acetyltransferase domain, is expressed in the colon and maps to cytoband 14q22.1. The protein localizes to the Golgi apparatus and the endosome. It is important for UDP-GlcNAc biosynthesis pathway. GNA1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.
Function:
Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 1/2.
Subcellular Location:
Golgi apparatus membrane. Endosome membrane.
Similarity:
Belongs to the acetyltransferase family.
GNA1 subfamily.
Contains 1 N-acetyltransferase domain.
SWISS:
Q96EK6
Gene ID:
64841
Database links:Entrez Gene: 64841 Human
Entrez Gene: 54342 Mouse
SwissProt: Q96EK6 Human
SwissProt: Q9JK38 Mouse
Unigene: 702056 Human
Unigene: 312945 Mouse
Unigene: 14702 Rat
Scan Wechat Qrcode
Scan Whatsapp Qrcode