Product Name	GMPR1
Chinese Name	鸟苷酸还原酶1抗体
Alias	GMP reductase 1; Gmpr; GMPR1_HUMAN; Guanosine monophosphate reductase 1; guanosine monophosphate reductase.
Research Area	Cell biology  Chromatin and nuclear signals  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	37kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GMPR1: 261-345/345
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.[provided by RefSeq, Oct 2009]. Function: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Subunit: Homotetramer. Similarity: Belongs to the IMPDH/GMPR family. SWISS: P36959 Gene ID: 2766 Database links: Entrez Gene: 2766 Human Entrez Gene: 66355 Mouse Entrez Gene: 117533 Rat Omim: 139265 Human SwissProt: P36959 Human SwissProt: Q9DCZ1 Mouse SwissProt: Q9Z244 Rat Unigene: 484741 Human Unigene: 290802 Mouse Unigene: 3862 Rat

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