Product Name	GLYCTK
Chinese Name	HBeAgBinding protein4/甘油激酶抗体
Alias	HBEBP2; CG9886 like; GLCTK_HUMAN; Glycerate kinase; Glyctk; GLYCTK; HBeAg binding protein 2; HBeAg binding protein 4; HBeAg-binding protein 4; HBeAgBP4A; HBEBP2; HBEBP4.
Research Area	Cell biology  Neurobiology  Signal transduction  Stem cells  Bacteria and viruses  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	55kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human HBEBP2/GLYCTK: 251-350/523
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This locus encodes a member of the glycerate kinase type-2 family. The encoded enzyme catalyzes the phosphorylation of (R)-glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated with the disease D-glyceric aciduria. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009] Subcellular Location: Cytoplasm and Cytoplasm. Mitochondrion. Tissue Specificity: Widely expressed. DISEASE: Defects in GLYCTK are the cause of D-glyceric aciduria (D-GA) [MIM:220120]. D-GA is a rare metabolic disease characterized by chronic metabolic acidosis and a highly variable clinical phenotype. Clinical features range from an encephalopathic presentation with seizures, microcephaly, severe mental retardation and early death, to milder manifestations with only speech delay or even normal development. Similarity: Belongs to the glycerate kinase type-2 family. SWISS: Q8IVS8 Gene ID: 132158 Database links: Entrez Gene: 132158 Human Entrez Gene: 235582 Mouse Entrez Gene: 684314 Rat Omim: 610516 Human SwissProt: Q9BE01 Cynomolgus Monkey SwissProt: Q8IVS8 Human SwissProt: Q8QZY2 Mouse SwissProt: Q0VGK3 Rat Unigene: 415312 Human Unigene: 335420 Mouse Unigene: 202605 Rat
Product Picture	Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti- GLYCTK (SL13448R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 52 kD

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