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Product Name GSTK1 Chinese Name 谷胱甘肽S转移酶κ抗体 Alias Glutathione S Transferase kappa 1; EC 2.5.1.18; Glutathione S transferase subunit 13; Glutathione S-transferase k1; Glutathione S-transferase kappa 1; Glutathione S-transferase subunit 13; Glutathione S-transferase subunit 13 homolog; GST 13 13; GST 13-13; GST; GST class kappa; GST class-kappa; GST13; GST13-13; GSTK1 1; Gstk1; GSTK1-1; GSTK1_HUMAN; hGSTK1. Research Area Cell biology The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 25kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Glutathione S Transferase kappa 1: 9-80/226 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Members of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. There are eight families of GST proteins, namely alpha, zeta, theta, kappa, mu, pi, sigma and omega, each of which are composed of proteins that have a variety of functions throughout the cell. GSTK1 (glutathione S-transferase kappa 1), also known as glutathione S-transferase subunit 13 (GST 13-13) or GSTK1-1, is a 226 amino acid ubiquitously expressed protein belonging to the kappa class of the GST superfamily that functions in cellular detoxification. Localizing to peroxisome, GSTK1 exists as a homodimer that catalyzes the conjugation of glutathione to a number of hydrophobic substrates leading to their removal from the cell.
Function:
Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB).
Subunit:
Homodimer.
Subcellular Location:
Peroxisome.
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the GST superfamily. Kappa family.
SWISS:
Q9Y2Q3
Gene ID:
373156
Database links:Entrez Gene: 373156 Human
Entrez Gene: 76263 Mouse
Omim: 602321 Human
SwissProt: Q9Y2Q3 Human
SwissProt: Q9DCM2 Mouse
Unigene: 390667 Human
Unigene: 267014 Mouse
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