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Product Name TFAR19/PDCD5 Chinese Name 凋亡相关蛋白5抗体 Alias TF-1 cell apoptsis-related gene 19; Programmed cell death protein 5; TF-1 cell apoptosis-related protein 19; Protein TFAR19; PDCD5. Research Area Tumour Cell biology Developmental biology Apoptosis Immunogen Species Rabbit Clonality Polyclonal React Species Human, Rat, (predicted: Mouse, Chicken, Dog, Cow, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 14kDa Cellular localization The nucleus cytoplasmic Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human TFAR19: 45-125/125 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a protein expressed in tumor cells during apoptosis independent of the apoptosis-inducing stimuli. Prior to apoptosis induction, this gene product is distributed in both the nucleus and cytoplasm. Once apoptosis is induced, the level of this protein increases and by relocation from the cytoplasm, it accumulates in the nucleus. Although its exact function is not defined, this protein is thought to play an early and universal role in apoptosis.
Tissue Specificity:
Widely expressed. Highest levels in heart, testis, kidney, pituitary gland, adrenal gland and placenta.
Similarity:
Belongs to the PDCD5 family.
SWISS:
O14737
Gene ID:
9141
Database links:Entrez Gene: 9141 Human
Entrez Gene: 100042424 Mouse
Entrez Gene: 56330 Mouse
Omim: 604583 Human
SwissProt: O14737 Human
SwissProt: P56812 Mouse
Unigene: 443831 Human
Unigene: 371609 Mouse
Unigene: 440265 Mouse
凋亡相关蛋白TFAR19又称PDCD5,是新近发现的与促凋亡有关的凋亡相关蛋白,目前主要用于TumourApoptosis方面的研究。Product Picture Paraformaldehyde-fixed, paraffin embedded (rat testis tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PDCD5) Polyclonal Antibody, Unconjugated (SL1333R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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