Product Name	FVT1
Chinese Name	滤泡型Transporter1/II型慢性淋巴性白血病抗体
Alias	3 dehydrosphinganine reductase; 3 ketodihydrosphingosine reductase; 3-dehydrosphinganine reductase; 3-ketodihydrosphingosine reductase; DHSR; FLJ36555; FLJ92680; Follicular lymphoma variant translocation 1; Follicular variant translocation protein 1; FVT 1; FVT-1; FVT1; KDS reductase; KDSR; KDSR_HUMAN; SDR35C1; Short chain dehydrogenase/reductase family 35C member 1.
Research Area	Tumour  Cell biology  Transporter  Cell type markers  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	33kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human FVT1: 41-140/332
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS). Function: Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS). Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Expressed in all tissues examined. Highest expression in placenta. High expression in lung, kidney, stomach and small intestine, low expression in heart, spleen and skeletal muscle. Weakly expressed in normal hematopoietic tissues. Higher expression in some T-cell malignancies and PHA-stimulated lymphocytes. DISEASE: Note=A chromosomal aberration involving KDSR is a cause of follicular lymphoma; also known as type II chronic lymphatic leukemia. Translocation t(2;18)(p11;q21) with a Ig J kappa chain region. Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. SWISS: Q06136 Gene ID: 2531 Database links: Entrez Gene: 505558 Cow Entrez Gene: 2531 Human Entrez Gene: 70750 Mouse Entrez Gene: 360833 Rat Omim: 136440 Human SwissProt: Q2KIJ5 Cow SwissProt: Q06136 Human SwissProt: Q6GV12 Mouse

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