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Rabbit Anti-FSD1 antibody
Rabbit Anti-FSD1 antibody
Fibronectin type 3 and SPRY (spla, ryanodine) domain containing (with coiled-coil motif) 1; Fibronectin type 3 and SPRY domain containing 1; Fibronectin type III and SPRY domain containing 1; Fibronectin type III and SPRY domain-containing protein 1; Fibr
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  • NO.:SL13220R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,Rat,(predicted: Human,Dog,Pig,Cow,Horse,Sheep,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Product Name FSD1
Chinese Name FSD1蛋白抗体
Alias Fibronectin type 3 and SPRY (spla, ryanodine) domain containing (with coiled-coil motif) 1; Fibronectin type 3 and SPRY domain containing 1; Fibronectin type III and SPRY domain containing 1; Fibronectin type III and SPRY domain-containing protein 1; Fibronectin type III and SPRY domains containing protein 1; FSD1; FSD1_HUMAN; GLFND; MGC3213; MGC58341; Microtubule-associated protein GLFND; MID1-related protein 1; midline 1-related protein 1; MIR1; VLP27.  
Research Area Cell biology  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 56kDa
Cellular localization The nucleus cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human FSD1: 421-496/496 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail May be involved in microtubule organization and stabilization.

Function:
May be involved in microtubule organization and stabilization.

Subunit:
Oligomerization is required for binding to microtubules.

Subcellular Location:
Cytoplasm > cytoskeleton > centrosome. Nucleus. Cytoplasm. Cleavage furrow. Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle.

Tissue Specificity:
Highly expressed in brain tissues, including cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Lower expression in spinal chord.

Similarity:
Contains 1 B30.2/SPRY domain.
Contains 1 COS domain.
Contains 1 fibronectin type-III domain.

SWISS:
Q9BTV5

Gene ID:
79187

Database links:

Entrez Gene: 79187 Human

Entrez Gene: 240121 Mouse

Omim: 609828 Human

SwissProt: Q05B84 Cow

SwissProt: Q9BTV5 Human

SwissProt: Q7TPM6 Mouse

Unigene: 28144 Human

Unigene: 270660 Mouse



Product Picture
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FSD1) Polyclonal Antibody, Unconjugated (SL13220R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FSD1) Polyclonal Antibody, Unconjugated (SL13220R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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