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Product Name FSD1 Chinese Name FSD1蛋白抗体 Alias Fibronectin type 3 and SPRY (spla, ryanodine) domain containing (with coiled-coil motif) 1; Fibronectin type 3 and SPRY domain containing 1; Fibronectin type III and SPRY domain containing 1; Fibronectin type III and SPRY domain-containing protein 1; Fibronectin type III and SPRY domains containing protein 1; FSD1; FSD1_HUMAN; GLFND; MGC3213; MGC58341; Microtubule-associated protein GLFND; MID1-related protein 1; midline 1-related protein 1; MIR1; VLP27. Research Area Cell biology Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, Rat, (predicted: Human, Dog, Pig, Cow, Horse, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 56kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FSD1: 421-496/496 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail May be involved in microtubule organization and stabilization.
Function:
May be involved in microtubule organization and stabilization.
Subunit:
Oligomerization is required for binding to microtubules.
Subcellular Location:
Cytoplasm > cytoskeleton > centrosome. Nucleus. Cytoplasm. Cleavage furrow. Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle.
Tissue Specificity:
Highly expressed in brain tissues, including cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Lower expression in spinal chord.
Similarity:
Contains 1 B30.2/SPRY domain.
Contains 1 COS domain.
Contains 1 fibronectin type-III domain.
SWISS:
Q9BTV5
Gene ID:
79187
Database links:Entrez Gene: 79187 Human
Entrez Gene: 240121 Mouse
Omim: 609828 Human
SwissProt: Q9BTV5 Human
SwissProt: Q7TPM6 Mouse
Unigene: 28144 Human
Unigene: 270660 Mouse
Product Picture Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FSD1) Polyclonal Antibody, Unconjugated (SL13220R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FSD1) Polyclonal Antibody, Unconjugated (SL13220R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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