Product Name	FNDC4
Chinese Name	Ⅲ型纤维连接蛋白域蛋白4抗体
Alias	Fibronectin type III domain containing 4; Fibronectin type III domain containing protein 4; Fibronectin type III domain-containing protein 4; Fibronectin type III repeat containing protein 1; Fibronectin type III repeat-containing protein 1; FLJ22362; FNDC 4; FNDC4; FNDC4_HUMAN; FRCP 1; FRCP1.
literatures	Specific References  (2)     |     SL13192R has been referenced in 2 publications. [IF=4.452] Baolin Wang. et al. FNDC4 acts as an extracellular factor to promote the invasiveness of hepatocellular carcinoma partly via the PI3K/Akt signalling pathway. 2021 Aug 21  IHC ;  Human.   PubMed:34418326 [IF=3.694]  Zhao Wang . et al. Fibronectin type III domain-containing 4 promotes the migration and differentiation of bovine skeletal muscle-derived satellite cells via focal adhesion kinase. Cell Adhes Migr. 2020;14(1):153-164  WB,IF,IP ;  Bovine.   PubMed:32881638
Research Area	Cell biology  Cell adhesion molecule  Cell differentiation
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	21kDa
Cellular localization	The cell membrane Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human FNDC4: 101-200/234 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Fibronectins are multi-domain glycoproteins that bind to a variety of substances including collagen, actin, heparin, DNA, fibrin and fibronectin receptors. They are involved in a diverse array of important functions such as blood coagulation, wound healing, cell adhesion, cell differentiation and migration. FNDC4 (Fibronectin type III domain-containing protein 4), also known as FRCP1 (Fibronectin type III repeat-containing protein 1), is a 234 amino acid membrane protein that contains one fibronectin type-III domain, which serves as a binding site for DNA, heparin or the cell surface. The gene encoding FNDC4 is localized to human chromosome two, which houses over 1,400 genes and comprises nearly 8% of the human genome. Subcellular Location: Membrane; Single-pass type I membrane protein (Potential). Similarity: Contains 1 fibronectin type-III domain. SWISS: Q9H6D8 Gene ID: 64838 Database links: Entrez Gene: 64838 Human Entrez Gene: 64339 Mouse GenBank: NP_073734.1 Human Omim: 611905 Human SwissProt: A6QPL2 Cow SwissProt: Q9H6D8 Human SwissProt: Q3TR08 Mouse Unigene: 27836 Human Unigene: 732184 Human Unigene: 292544 Mouse

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