Product Name	Oxytocin R
Chinese Name	催产素受体(缩宫素受体)抗体
Alias	OXYR_HUMAN; Oxytocin receptor; OXTR; OTR1; OT-R; OTR; OT R; OTR 1; OXT R;
literatures	Specific References  (12)     |     SL1314R has been referenced in 12 publications. [IF=8.008] Kaho Nakamura. et al. Probing the Spatiotemporal Dynamics of Oxytocin in the Brain Tissue Using a Simple Peptide Alkyne-Tagging Approach. ANAL CHEM. 2022;94(35):11990–11998  IHC ;  Mouse.   PubMed:36008880 [IF=4.966] Korie Sondgeroth. et al. The Endometrium Contributes to the Differential Contractile Response to Oxytocin of Uterine Tissue from Virgin and Proven Breeder Non-pregnant Rats. 2021 May 14  IHC ;  Rat.   PubMed:10.1096/fasebj.2021.35.S1.05268 [IF=4.473] Tomoki Kumagai. et al. Oxytocin suppresses CXCL10 production in TNF-α-stimulated human dental pulp stem cells. CELL BIOL INT. 2022 Jul;46(9):1530-1535  ICC, WB ;  Human.   PubMed:35870165 [IF=4.249] Zoratto, F. et al.Intranasal oxytocin administration promotes emotional contagion and reduces aggression in a mouse model of callousness. (2018) Neuropharmacology.Sep 10;143:250-267.  IHC ;  mouse.   PubMed:30213592 [IF=4.2] Zhang, Fengwei, et al. "Seasonal Expression of Oxytocin and Oxytocin Receptor in the Scented Gland of Male Muskrat (Ondatra zibethicus)." Scientific Reports 7.1 (2017): 16627.  WB, IHC-P ;  Others.   PubMed:29192229 [IF=3.932] Ali II et al. Oxytocin induces intracellular Ca2+ release in cardiac fibroblasts from neonatal rats. Cell Calcium. 2019 Oct 4;84:102099.  ICF ;  Rat.   PubMed:31614270 [IF=2.445] Yuan Z et al. Seasonal expressions of oxytocin and oxytocin receptor in the epididymides in the wild ground squirrels (Citellus Dauricus Brandt). Gen Comp Endocrinol. 2020 Apr 1;289:113391.  WB&IHC-P ;  Wild ground squirrel.   PubMed:31917151 [IF=2.15] Huang, Miaomaio, et al. "The abnormal expression of oxytocin receptors in the uterine junctional zone in women with endometriosis." Reproductive Biology and Endocrinology 15.1 (2017): 1.  IHC-P ;  Human.   PubMed:28049501 [IF=2.136] Liu Q et al. Seasonal expressions of oxytocin and oxytocin receptor in epididymis of the male muskrat (Ondatra zibethicus).(2018) Theriogenology.124:24-31.  IHC ;  muskrat.   PubMed:30336300 [IF=2] Zhang, Ying, et al. "Expression of oxytocin receptors in the uterine junctional zone in women with adenomyosis." Acta Obstetricia et Gynecologica Scandinavica (2015).  IHC-P ;  Human.   PubMed:25627343 [IF=1.974] Raihana Nasrin Ferdousy. et al. Anti-Müllerian hormone stimulates expression of the collagen-specific chaperone 47-kDa heat shock protein in bovine uterine epithelial cells. ANIM SCI J. 2022 Dec;93(1):e13787  IHC ;  Bovine.   PubMed:36507591 [IF=0] Lim JS et al. Effects of Oxytocin on Cell Proliferation in a Corticotroph Adenoma Cell Line. Endocrinol Metab (Seoul). 2019 Sep;34(3):302-313.  IHC-P&ICF ;  Mouse&Rat.   PubMed:31565883
Research Area	Neurobiology  Growth factors and hormones  The cell membrane受体  Endocrinopathy
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	43kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse oxytocin receptor: 325-388/388 <Cytoplasmic>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	he protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008] Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. SWISS: P97926 Gene ID: 18430 Database links: Entrez Gene: 281371 Cow Entrez Gene: 5021 Human Entrez Gene: 18430 Mouse Entrez Gene: 397092 Pig Entrez Gene: 25342 Rat Omim: 167055 Human SwissProt: P56449 Cow SwissProt: P30559 Human SwissProt: P97926 Mouse SwissProt: P32306 Pig SwissProt: P70536 Rat SwissProt: Q28756 Sheep Unigene: 2820 Human Unigene: 333310 Mouse Unigene: 6841 Rat OTR在人的子宫平滑肌The cell membrane上有缩宫素受体，缩宫素引起子宫收缩的机制可能是通过激活缩宫素受体而实现的。经研究发现，缩宫素受体在外周组织和中枢神经系统内均有分布。缩宫素与不同组织、细胞上的缩宫素受体结合，通过多种Signal transduction途径而发挥作用。
Product Picture	Sample: Brain (Mouse) Lysate at 40 ug Primary: Anti-Oxytocin R (SL1314R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 43 kD Observed band size: 53 kD Sample: Lane 1: Ovary (Mouse) Lysate at 40 ug Lane 2: Cerebrum (Rat) Lysate at 40 ug Lane 3: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-Oxytocin R (SL1314R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 42 kD

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