TEL: +86 571 56623320 EMAIL: [email protected]
Product Name ETNK2 Chinese Name 乙醇胺激酶2抗体 Alias 4933417N20Rik; AI197444; EC 2.7.1.82; EKI 2; EKI2; EKI2_HUMAN; Ethanolamine kinase 2; Ethanolamine kinase like protein; Ethanolamine kinase-like protein; ETNK 2; ETNK2; FLJ10761; HMFT1716; RP11 74C13.2; Tuc1. Research Area Cell biology Signal transduction The new supersedes the old Transmembrane protein Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 45kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ETNK2/Ethanolamine kinase 2: 21-120/386 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Ethanolamine kinase 2, also known as EKI2, ETNK2 or HMFT1716, is a 386 amino acid protein that belongs to the choline/ethanolamine kinase family. Via the cytidine diphosphate (CDP) ethanolamine pathway, Ethanolamine kinase 2 catalyses the initial step of phosphatidylethanolamine (PtdEtn) biosynthesis. Ethanolamine kinase 2 is expressed in kidney, liver, testis, ovary and prostate, and is highly specific for ethanolamine phosphorylation. Upregulated during testis development, Ethanolamine kinase 2 may play an essential role in regulating placental hemostasis. Existing as three alternatively spliced isoforms, the gene encoding Ethanolamine kinase 2 maps to human and mouse chromosome 1. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
Function:
Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity.
Subcellular Location:
Belongs to the choline/ethanolamine kinase family.
Tissue Specificity:
Expressed in kidney, liver, ovary, testis and prostate.
Similarity:
Belongs to the choline/ethanolamine kinase family.
SWISS:
Q9NVF9
Gene ID:
64123
Database links:Entrez Gene: 55224 Human
Entrez Gene: 214253 Mouse
Omim: 609859 Human
SwissProt: Q9NVF9 Human
SwissProt: A7MCT6 Mouse
Unigene: 497469 Human
Unigene: 52111 Mouse
Unigene: 65516 Rat
Scan Wechat Qrcode