Product Name	ENOSF1
Chinese Name	烯醇化酶超家族成员1抗体
Alias	Enolase superfamily member 1; ENOSF 1; HSRTSBETA; RTS alpha; RTS; RTS beta; RTS beta protein; TYMSAS;
Research Area	Tumour  Cell biology  Signal transduction  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Dog, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	50kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ENOSF1: 351-443/443
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The rTS gene codes for a naturally occurring antisense RNA to thymidylate synthase (TS) mRNA and two proteins (rTSalpha and rTSbeta (also known as ENOSF1)). The role of the major protein product of rTS, ENOSF1 has been linked to alterations in TS protein expression, but the precise function of ENOSF1 is unknown. Expression of rTS is associated with growth arrest in cell culture, but its overexpression has been noted in cells resistant to anticancer drugs such as 5-fluorouracil and methotrexate. Studies have shown that increased expression of ENOSF1 is associated with the decrease in TS protein expression due to production of novel, diffusible signal molecules. Function: May regulate thymidylate synthase activity. Subcellular Location: Mitochondrial. Post-translational modifications: Could be sumoylated. Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. ENOSF1 subfamily. SWISS: Q7L5Y1 Gene ID: 55556 Database links: Entrez Gene: 615106 Cow Entrez Gene: 480185 Dog Entrez Gene: 100146163 Horse Entrez Gene: 55556 Human Entrez Gene: 100341613 Rabbit SwissProt: Q7L5Y1 Human Unigene: 658550 Human Unigene: 731510 Human Unigene: 732707 Human

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