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Product Name FABP12 Chinese Name 脂肪酸Binding protein12抗体 Alias FABP12; Fatty acid binding protein ORF; Fatty acid-binding protein 12; FBP12_HUMAN; Intracellular fatty acid binding protein FABP12; Probable fatty acid binding protein ENSP00000353650. Research Area Cell biology Signal transduction Binding protein The new supersedes the old Transmembrane protein Immunogen Species Rabbit Clonality Polyclonal React Species Human, Mouse, (predicted: Rat, Dog, Cow, Horse, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 16kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FABP12: 21-120/140 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABP12 (fatty acid-binding protein 12) is a 132 amino acid protein that belongs to the calycin superfamily and fatty-acid binding protein family. Highly expressed in adult retina and testis, FABP12 may function in lipid transport. The gene encoding FABP12 maps to mouse chromosome 3 A1.
Function:
May play a role in lipid transport.
Tissue Specificity:
Expressed in a number of retinoblastoma cell lines.
Similarity:
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
SWISS:
A6NFH5
Gene ID:
646486
Database links:Entrez Gene: 646486 Human
Entrez Gene: 75497 Mouse
SwissProt: A6NFH5 Human
SwissProt: Q9DAK4 Mouse
Product Picture Paraformaldehyde-fixed, paraffin embedded (Mouse testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FABP12) Polyclonal Antibody, Unconjugated (SL13064R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.Paraformaldehyde-fixed, paraffin embedded (Human colon carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FABP12) Polyclonal Antibody, Unconjugated (SL13064R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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