Product Name	DMWD
Chinese Name	强直性肌营养不良相关蛋白9抗体
Alias	dystrophia myotonica containing WD repeat motif; D19S593E; DM 9; DM9; DMR N9; DMR N9 protein; DMRN 9; DMRN9; DMWD; DMWD_HUMAN; Dystrophia myotonica containing WD repeat motif; Dystrophia myotonica containing WD repeat motif protein; Dystrophia myotonica WD repeat containing protein; Dystrophia myotonica WD repeat-containing protein; Dystrophia myotonica-containing WD repeat motif protein; Gene59; Protein 59; Protein DMR-N9.
Research Area	Cell biology  Neurobiology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Cow, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	70kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DMWD/DMRN9: 501-600/6754
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	DMWD is a 674 amino acid protein containing five WD repeats. DMWD may play a role in the development of mental symptoms in severe cases of myotonic dystrophy, a chronic multisystemic disease characterized by wasting of the muscles, heart conduction defects, cataracts, endocrine changes and myotonia. The DMWD gene is located upstream of the DMPK gene and is prominently expressed in tissues affected in myotonic dystrophy patients. DMWD may also contribute to regulation in meiosis. DMWD is expressed in kidney and spleen, with strongest expression in brain, liver and testis. The gene encoding DMWD maps to human chromosome 19q13.32 and mouse chromosome 7 A3. Function: Could have a regulatory function in meiosis. Subcellular Location: Contains 5 WD repeats. Tissue Specificity: Strongest expression in brain, liver, and testis. Also expressed in kidney and spleen. Similarity: Contains 5 WD repeats. SWISS: Q09019 Gene ID: 1762 Database links: Entrez Gene: 1762 Human Omim: 609857 Human SwissProt: Q09019 Human Unigene: 515474 Human

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