Product Name	DAPL1
Chinese Name	凋亡相关蛋白激酶样蛋白1抗体
Alias	dapL1; DAPL1_HUMAN; death associated protein-like 1; Death-associated protein-like 1; Early epithelial differentiation-associated protein; EEDA; RP23-151F21.4.
Research Area	Cell biology  Apoptosis  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Horse, )
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	12kDa
Cellular localization	The nucleus cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DAPL1: 1-100/107
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	In contrast to growth factors which promote cell proliferation, FAS ligand (FAS-L) and the tumor necrosis factors (TNFs) rapidly induce apoptosis. Cellular response to FAS-L and TNF is mediated by structurally related receptors containing a conserved cytoplasmic region called the “death domain”. DAPL1 (Death-associated protein-like 1), also known as EEDA (Early epithelial differentiation-associated protein), is a 107 amino acid protein that is expressed in hair follicles and is thought to function in a similar manner to DAP-1, possibly participating in the early stages of epithelial differentiation and/or apoptosis. Function: May play a role in the early stages of epithelial differentiation or in apoptosis. Tissue Specificity: Expressed in hair follicle (at protein level). SWISS: A0PJW8 Gene ID: 92196 Database links: Entrez Gene: 92196 Human Entrez Gene: 76747 Mouse SwissProt: A0PJW8 Human SwissProt: Q9D757 Mouse Unigene: 59761 Human Unigene: 275769 Mouse

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