Product Name	Defensin beta 2
Chinese Name	防御素β2/Defensin β2抗体
Alias	beta-defensin 2 precursor; beta Defensin 2; beta-defensin 2; Defb2; Q32ZI5_RAT; DFB4A_HUMAN.  Defensin β2.
literatures	Specific References  (2)     |     SL1296R has been referenced in 2 publications. [IF=3.365] Shalong Wang. et al. Bovine Lactoferrin Protects Dextran Sulfate Sodium Salt Mice Against Inflammation and Impairment of Colonic Epithelial Barrier by Regulating Gut Microbial Structure and Metabolites. Front Nutr. 2021; 8: 660598  WB,IF ;  Mouse.   PubMed:33954162 [IF=2.245] Renli Qi. et al. Changes of Gut Microbiota and Its Correlation With Short Chain Fatty Acids and Bioamine in Piglets at the Early Growth Stage. Front Vet Sci. 2020; 7: 617259  WB ;  Pig.   PubMed:33469555
Research Area	Microbiology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Rat, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	8kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from rat beta 2 Defensin: 21-71/71
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Jul 2008] Subcellular Location: Secreted. Tissue Specificity: Expressed in the skin and respiratory tract. Similarity: Belongs to the beta-defensin family. LAP/TAP subfamily. SWISS: Q32ZI5 Gene ID: 641631 Database links: 防御素在人体中广泛分布的，目前已知的α－防御素有6种，研究人员从人体的肾脏、气管、鼻粘膜与唾液中也发现了两种β防御素，在许多器官的epithelial cells与非上皮组织的细胞中发现了β－防御素。 Defensin β2在维持肌体天然免疫功能、介导炎症反应以及调节特异性免疫中的作用引起人们的重视，防御素的表达与病原体的入侵紧密相关。
Product Picture	Tissue/cell: human kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-beta 2 Defensin Polyclonal Antibody, Unconjugated(SL1296R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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