Product Name	Defensin beta 2
Chinese Name	防御素β2/Defensin β2抗体
Alias	beta Defensin 2; beta-defensin 2; mBD-2; Defensin, beta 2; Defb2; MGC129140; MGC129141; Skin-antimicrobial peptide 1; SAP1; BD-2; BD 2; BD2; Beta 4 Defensin; DEF B2; DEF B4; DEFB 102; DEFB 2; DEFB-2; DEFB 4; DEFB102; DEFB2; DEFB4; Defensin 4 beta; Defensin beta 4; HBD-2; HBD 2; HBD2; SAP 1; SAP1; Skin antimicrobial peptide 1; DFB4A_HUMAN; DEFB4A; DEFB2_MOUSE.  Defensin β2.
literatures	Specific References  (1)     |     SL1295R has been referenced in 1 publications. [IF=2.215] Karadag Remzi. et al. Effects of Different Doses of Systemic Isotretinoin on Eyes: A Histopathological and Immunohistochemical Study in Rats. Cornea. 2020 May;39(5):621-627  IHC ;  Rat.   PubMed:31842038
Research Area	Microbiology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	6kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse beta 2 Defensin: 21-71/71
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Jul 2008] Function: Has bactericidal activity. Subcellular Location: Secreted. Tissue Specificity: Kidney, uterus and to a lesser extent in heart. Similarity: Belongs to the beta-defensin family. SWISS: P82020 Gene ID: 13215 Database links: Entrez Gene: 13215 Mouse 防御素在人体中广泛分布的，目前已知的α－防御素有6种，研究人员从人体的肾脏、气管、鼻粘膜与唾液中也发现了两种β防御素，在许多器官的epithelial cells与非上皮组织的细胞中发现了β－防御素。 Defensin β2在维持机体天然免疫功能、介导炎症反应以及调节特异性免疫中的作用引起人们的重视，防御素的表达与病原体的入侵紧密相关。
Product Picture	Tissue/cell: mouse uterus tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Defensin-beta2/DEFB2/HBD-2 Polyclonal Antibody, Unconjugated(SL1295R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining Tissue/cell: mouse kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Defensin-beta2/DEFB2/HBD-2 Polyclonal Antibody, Unconjugated(SL1295R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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