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Rabbit Anti-phospho-MYB (Ser532)antibody
Rabbit Anti-phospho-MYB (Ser532)antibody
c-Myb (phospho S532); p-c-Myb (phospho S532); Avian myeloblastosis viral (v-myb) oncogene homolog; C myb; c-Myb; MYB_HUMAN; Proto-oncogene c-Myb; Transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog.
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  • NO.:SL12917R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name phospho-MYB (Ser532)
Chinese Name 磷酸化转录激活因子MYB抗体
Alias c-Myb (phospho S532); p-c-Myb (phospho S532); Avian myeloblastosis viral (v-myb) oncogene homolog; C myb; c-Myb; MYB_HUMAN; Proto-oncogene c-Myb; Transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog.  
Product Type Phosphorylated anti 
Research Area Tumour  Cell biology  Chromatin and nuclear signals  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 84kDa
Cellular localization The nucleus 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthesised phosphopeptide derived from human MYB around the phosphorylation site of Ser532: VE(p-S)PT 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

Function:
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

Subcellular Location:
Nucleus.

Post-translational modifications:
Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.
Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.

Similarity:
Contains 3 HTH myb-type DNA-binding domains.

SWISS:
P10242

Gene ID:
4602

Database links:

Entrez Gene: 317776 Cow

Entrez Gene: 4602 Human

Entrez Gene: 17863 Mouse

Entrez Gene: 498982 Rat

Omim: 189990 Human

SwissProt: P46200 Cow

SwissProt: P10242 Human

SwissProt: P06876 Mouse

Unigene: 606320 Human

Unigene: 52109 Mouse



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