Product Name	VOPP1
Chinese Name	EGFR扩增和过度表达蛋白抗体
Alias	ECop; EGFR-coamplified and overexpressed protein; GASP; Glioblastoma-amplified secreted protein; overexpressed in cancer; prosurvival protein 1; Putative NF-kappa-B-activating protein 055N; Vesicular; Vesicular, overexpressed in cancer, prosurvival protein 1; vopp1; VOPP1_HUMAN.
Research Area	Tumour  Cell biology  Apoptosis  transcriptional regulatory factor  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	17kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human VOPP1: 41-140/172 <Cytoplasmic>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	VOPP1 (Vesicular, Overexpressed In Cancer, Prosurvival Protein 1) is a Protein Coding gene. GO annotations related to this gene include signal transducer activity. Function: Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed. Subcellular Location: Cytoplasmic vesicle membrane. When overexpressed, localizes in the nucleus and perinuclear regions. Tissue Specificity: Widely expressed with highest levels in thymus and ovary. Similarity: Belongs to the VOPP1/ECOP family. SWISS: Q96AW1 Gene ID: 81552 Database links: Entrez Gene: 767861 Cow Entrez Gene: 81552 Human Entrez Gene: 232023 Mouse Entrez Gene: 362374 Rat Omim: 611915 Human SwissProt: A6QNZ8 Cow SwissProt: Q96AW1 Human SwissProt: Q8R1C3 Mouse SwissProt: Q5RDG5 Orangutan SwissProt: B5DEK8 Rat Unigene: 488307 Human

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