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Rabbit Anti-ARSI antibody
Rabbit Anti-ARSI antibody
Arylsulfatase family, member I; arylsulfatase I; ASI; EC 3.1.6; FLJ16069; ARSI_HUMAN.
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  • NO.:SL12530R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name ARSI
Chinese Name 芳香基硫酸酯酶家族蛋白1抗体
Alias Arylsulfatase family, member I; arylsulfatase I; ASI; EC 3.1.6; FLJ16069; ARSI_HUMAN.  
Research Area Cell biology  Signal transduction  Growth factors and hormones  The new supersedes the old  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 61kDa
Cellular localization cytoplasmic Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human ARSI: 101-200/569 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Sulfatases (EC 3.1.5.6), such as ARSI, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules (Sardiello et al., 2005 [PubMed 16174644]).[supplied by OMIM, Mar 2008].

Function:
Sulfatases such as ARSI, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules

Subcellular Location:
Endoplasmic reticulum and Secreted

Tissue Specificity:
Expressed in placenta, in embryonic stem cells, fetal eyes and lens.

Post-translational modifications:
The oxidation of Cys-93 residue to 3-oxoalanine (also known as C(alpha)-formylglycine) by SUMF1/Sulfatase-modifying factor 1, seems critical for catalytic activity.

Similarity:
Belongs to the sulfatase family.

SWISS:
Q5FYB1

Gene ID:
340075

Database links:

Entrez Gene: 340075 Human

Omim: 610009 Human

SwissProt: Q5FYB1 Human



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