Product Name	APOBEC1
Chinese Name	载LipoproteinB-mRNA编辑酶复合物1抗体
Alias	ABEC1_HUMAN; APOBEC 1; APOBEC1; Apolipoprotein B mRNA editing enzyme; Apolipoprotein B mRNA editing enzyme catalytic polypeptide 1; Apolipoprotein B mRNA editing enzyme complex 1; Apolipoprotein B mRNA-editing enzyme 1; BEDP; C->U-editing enzyme APOBEC-1; CDAR1; EC 3.5.4.; HEPR.
Research Area	Cell biology  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	28kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human APOBEC1: 1-100/236
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated by This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. [provided by RefSeq, Jul 2008]. Function: Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. Subunit: Homodimer. Part of the apolipoprotein B mRNA editing complex with A1CF. Found in a complex with CELF2/CUGBP2 and A1CF. Interacts with HNRPAB and SYNCRIP. Subcellular Location: Cytoplasm. Tissue Specificity: Expressed exclusively in the small intestine. Similarity: Belongs to the cytidine and deoxycytidylate deaminase family. SWISS: P41238 Gene ID: 339 Database links: Entrez Gene: 339 Human Entrez Gene: 11810 Mouse GenBank: L25877 Human GenBank: U21951 Mouse Omim: 600130 Human SwissProt: P41238 Human SwissProt: P51908 Mouse SwissProt: Q694B3 Orangutan Unigene: 560 Human Unigene: 3333 Mouse

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