Product Name	Alpha SNAP
Chinese Name	可溶性附着蛋白α-SNAP抗体
Alias	Alpha soluble NSF attachment protein; Alpha-soluble NSF attachment protein; N ethylmaleimide sensitive factor attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein alpha; NAPA; SNAA_HUMAN; SNAP alpha; SNAP alpha; SNAP-alpha; SNAPA.
Research Area	Cell biology  Signal transduction  Transporter
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	33kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Alpha SNAP: 201-295/295
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAP 25 (synaptosomal-associated protein of 25kDa), SNAPs (soluble NSF attachment proteins) and synaptotagmin. VAMPs (also designated synaptobrevins), including VAMP-1 and VAMP-2, and synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. Function: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Subunit: Interacts with PRKCABP, and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. Found in a complex with VAMP8 (By similarity). Component of a SNARE-like complex that contains at least ZW10, USE1L, RINT1, STX18 and NAPA/SNAP-alpha. Interacts with VTI1A. Interacts with STX12 (By similarity). Subcellular Location: Membrane; Peripheral membrane protein. Similarity: Belongs to the SNAP family. SWISS: P54920 Gene ID: 8775 Database links: Entrez Gene: 518407 Cow Entrez Gene: 8775 Human Entrez Gene: 108124 Mouse Entrez Gene: 140673 Rat Omim: 603215 Human SwissProt: P81125 Cow SwissProt: P54920 Human SwissProt: Q9DB05 Mouse SwissProt: P54921 Rat Unigene: 126938 Human Unigene: 727492 Human Unigene: 104540 Mouse Unigene: 431371 Mouse Unigene: 31745 Rat

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