Product Name	SNX10
Chinese Name	分选连接蛋白10抗体
Alias	2410004M09Rik; MGC109202; MGC33054; SNX10; SNX10_HUMAN; Sorting nexin 10; Sorting nexin-10.
Research Area	Cell biology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	24kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SNX10: 11-100/201
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Sorting nexin (SNX) proteins are members of a large family of hydrophilic PX (phospholipid-binding motif) domain-containing proteins that interact with a variety of receptor types. SNXs are widely expressed, although the tissue distribution of each SNX mRNA varies. The ability of SNXs to bind specific phospholipids, as well as their tendency to form protein-protein complexes, suggests a role for these proteins in cellular membrane trafficking and protein sorting. SNXs may also function specifically in pro-degradative sorting, internalization, endosomal recycling or simply in endosomal sorting. SNX10 (Sorting nexin-10) is a 201 amino acid protein that contains one phox domain and belongs to the SNX family. Like other members of the SNX family, SNX10 is thought to play a role in intracellular trafficking events throughout the cell. Function: May be involved in several stages of intracellular trafficking (By similarity). May play a role in endosome homeostasis. Overexpression causes formation of huge vacuoles. Subcellular Location: Cytoplasm. Endosome membrane. Similarity: Belongs to the sorting nexin family. Contains 1 PX (phox homology) domain. SWISS: Q9Y5X0 Gene ID: 29887 Database links: Entrez Gene: 508836 Cow Entrez Gene: 29887 Human Entrez Gene: 71982 Mouse Entrez Gene: 297096 Rat SwissProt: Q0IIL5 Cow SwissProt: Q9Y5X0 Human SwissProt: Q9CWT3 Mouse SwissProt: Q5BJX4 Rat
Product Picture	Sample: Kidney (Mouse) Lysate at 40 ug Heart (Mouse) Lysate at 40 ug Primary: Anti-SNX10 (SL12408R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 24 kD Observed band size: 24 kD

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