Product Name	CFDP1
Chinese Name	颅面部发育蛋白1抗体
Alias	BCNT; Bucentaur; CENP-29; CP27; Craniofacial development protein 1; p97; Phosphoprotein (Bucentaur); SWC5; Yeti; CFDP1_HUMAN.
Research Area	Developmental biology  Stem cells
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	34kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CFDP1: 131-230/299
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	CFDP1 is a 299 amino acid protein that is involved in embryogenesis and normal cell function. When treated with CFDP1 peptide, mouse molar teeth increase in size, whereas treating cells with antibodies against CFDP1 shows an increase in the number of apoptotic cells and gradual tooth disintegration. CFDP1 is highly expressed in developing mouse teeth and is expressed at lower levels in liver, lung and heart. The gene encoding CFDP1 maps to human chromsome 16, in a region that has been associated with inherited craniofacial diseases, such as fanconi anemia type A. There are two isoforms of CFDP1 that are produced as a result of alternative splicing events. Function: May play a role during embryogenesis (By similarity). Tissue Specificity: Ubiquitous. Post-translational modifications: Phosphorylated by CK2 (casein kinase II) in vitro. Similarity: Contains 1 BCNT-C domain. SWISS: Q9UEE9 Gene ID: 10428 Database links: Entrez Gene: 10428 Human Entrez Gene: 23837 Mouse Entrez Gene: 292027 Rat Omim: 608108 Human SwissProt: Q8HXY9 Cow SwissProt: Q9UEE9 Human SwissProt: O88271 Mouse SwissProt: Q75UQ2 Rat

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