Product Name	TCP1 alpha
Chinese Name	分子伴侣复合体TCP-1α抗体
Alias	AI528772; c-cpn; CCT alpha; CCT; CCT-alpha; CCT1; Ccta; CCTalpha; D6S230E; MGC133746; p63; T complex 1; T complex locus TCP 1; T complex protein 1 alpha subunit; T complex protein 1; T-complex homolog TCP1; T-complex protein 1 subunit alpha; T-complex protein 1 subunit alpha B; Tailless complex polypeptide 1; Tailless complex polypeptide 1A; Tailless complex polypeptide 1B; TCP 1 alpha; Tcp-1; TCP-1-alpha; TCP1; TCPA_HUMAN; Tp63; TRic.
Research Area	Cell biology  Signal transduction  Cytoskeleton
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	60kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from Human TCP1 alpha: 225-340/556
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. Subunit: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG. Component of the BBS/CCT complex composed at least of MKKS, BBS10, BBS12, TCP1, CCT2, CCT3, CCT4, CCT5 AND CCT8. Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Similarity: Belongs to the TCP-1 chaperonin family. SWISS: P17987 Gene ID: 6950 Database links: Entrez Gene: 512043 Cow Entrez Gene: 42649 Drosophila melanogaster Entrez Gene: 6950 Human Entrez Gene: 21454 Mouse Entrez Gene: 100153485 Pig Entrez Gene: 100302435 Rabbit Entrez Gene: 24818 Rat Entrez Gene: 851798 Saccharomyces cerevisiae Omim: 186980 Human SwissProt: Q32L40 Cow SwissProt: P12613 Drosophila melanogaster SwissProt: P17987 Human SwissProt: P11983 Mouse SwissProt: P28480 Rat SwissProt: P12612 Saccharomyces cerevisiae
Product Picture	Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti- TCP1 alpha (SL12292R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 60 kD

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