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Product Name GPR64 Chinese Name G protein-coupled receptor64抗体 Alias Epididymis specific protein 6; FLJ00282; G protein coupled receptor 64; G protein coupled receptor epididymis specific; GPR 64; GPR64; HE 6; He 6 receptor; HE6; He6 receptor; MGC104454; MGC138738; MGC138739; TM7LN2; GPR64_HUMAN; GPCR GPR64. Research Area Developmental biology Stem cells transcriptional regulatory factor G protein-coupled receptor G protein signal Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 112kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human G protein coupled receptor 64: 55-170/1017 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This orphan B G-protein coupled receptor could be involved in a signal transduction pathway controlling epidymal function and male fertility: it has been reported in the epididymis. ESTs have been isolated from embryo, kidney, placenta, skeletal muscle and testis libraries.
Function:
Could be involved in a signal transduction pathway controlling epididymal function and male fertility.
Subunit:
Forms a heterodimer, consisting of a large extracellular region linked to a seven-transmembrane moiety (Probable).
Subcellular Location:
Cell membrane; Multi pass membrane protein.
Tissue Specificity:
Epididymis specific. Both subunits were associated with apical membranes of efferent ductule and proximal epididymal duct epithelia.
Post-translational modifications:
Proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit (Potential).
Similarity:
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 1 GPS domain.
SWISS:
Q8IZP9
Gene ID:
10149
Database links:
Entrez Gene: 10149 Human
Omim: 602657 Human
SwissProt: Q8IZP9 Human
Unigene: 421137 Human
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