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Product Name ZFP57 Chinese Name Zinc finger protein57抗体 Alias C6orf40; TNDM1; Zinc Finger Protein 57; ZNF698; ZNF57_HUMAN. Research Area Developmental biology Stem cells transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 64kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from Human ZFP57: 64-165/555 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail ZFP57 is a 452 amino acid protein that contains one KRAB domain and seven C2H2-type zinc fingers and is a member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZFP57 functions as a transcriptional repressor that inhibits the expression of Schwann cell-specific proteins, thereby playing a role in the development of the peripheral nervous system. ZFP57 exists as two isoforms that are produced from alternative splicing events.
Function:
Zfp57 is a putative transcription factor that is a marker of mouse embryonic stem cell pluripotency, the expression of which decreases in the absence of LIF.
Subcellular Location:
Nuclear
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 13 C2H2-type zinc fingers.
Contains 1 KRAB domain.
SWISS:
Q68EA5
Gene ID:
126295
Database links:Entrez Gene: 126295 Human
Omim: 612192 Human
SwissProt: Q68EA5 Human
Unigene: 591378 Human
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