Product Name	ZNF426
Chinese Name	Zinc finger protein426抗体
Alias	HGNC:20725; MGC2663; zinc finger protein 426; ZN426_HUMAN; Znf426.
Research Area	transcriptional regulatory factor  Zinc finger protein  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Rabbit, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	63kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from Human ZNF426: 421-520/554
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF426 (Zinc finger protein 426), also known as MGC2663, is a 554 amino acid protein that is thought to be involved in transcriptional regulation. Localized to the nucleus, ZNF426 contains one KRAB domain and 12 C2H2-type zinc fingers through which it may convey DNA, RNA and protein binding capabilities. Specifically, ZNF426 may interact with the viral protein KSHV ORF 50 and, through this interaction, may activate viral gene transcription. Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus. Similarity: Contains 12 C2H2-type zinc fingers. Contains 1 KRAB domain. SWISS: Q9BUY5 Gene ID: 79088 Database links: Entrez Gene: 79088 Human Entrez Gene: 235028 Mouse Entrez Gene: 690895 Rat SwissProt: Q9BUY5 Human SwissProt: Q8R1D1 Mouse SwissProt: A1L1L7 Rat Unigene: 594011 Human Unigene: 297660 Mouse Unigene: 120278 Rat

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