Product Name	HOXC4
Chinese Name	同源盒蛋白C4抗体
Alias	CP 19; CP19; Homeo box 3E; Homeo box C4; Homeo box protein HoxC4; Homeobox 3E; Homeobox C4; Homeobox protein CP19; Homeobox protein Hox C4; Homeobox protein Hox-3E; Homeobox protein Hox-C4; Homeobox protein HoxC4; Homeobox3E; HomeoboxC4; HOX 3; Hox 3E; HOX C4; HOX3; Hox3E; HOXC 4; Hoxc4; HXC4_HUMAN.
Research Area	Cell biology  Developmental biology  Signal transduction  transcriptional regulatory factor  Cell differentiation
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Zebrafish, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	30kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human HOXC4: 181-264/264
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Homeobox (HOX) genes, which share a highly conserved 183-bp sequence, encode proteins capable of binding to specific DNA sequences and functioning as transcription factors. During embryogenesis, HOX genes play a critical role in the spatial and temporal differentiation of cells. HoxC4, a sequence-specific transcription factor, belongs to the Antp HOX family and localizes to the nucleus. It functions as a part of a developmental regulatory system, providing cells with specific positional identities on the anterior-posterior axis. HoxC4 expression levels increase with differentiation of lymphoid cells, suggesting its role in the molecular regulation of hematopoiesis. HoxC4 is also expressed in differentiated keratinocytes. Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Subcellular Location: Nucleus. Similarity: Belongs to the Antp homeobox family. Deformed subfamily. Contains 1 homeobox DNA-binding domain. SWISS: P09017 Gene ID: 3221 Database links: Entrez Gene: 613740 Cow Entrez Gene: 3221 Human Entrez Gene: 15423 Mouse Entrez Gene: 24459 Rat Entrez Gene: 30345 Zebrafish Omim: 142974 Human SwissProt: P09017 Human SwissProt: Q08624 Mouse SwissProt: P18865 Rat SwissProt: Q9PWM3 Zebrafish

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