Product Name	HOXB6
Chinese Name	同源盒蛋白B6抗体
Alias	HGNC:5117; homeo box B6; Homeobox protein Hox B6; Hox-2.2; HOX2; HOX2B; HU-2; HXB6_HUMAN.
Research Area	Tumour  Cell biology  Developmental biology  transcriptional regulatory factor  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Cow, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	25kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human HOXB6: 145-224/224
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	HoxB6 is cytoplasmically expressed throughout fetal epidermal development, but displays nuclear expression in normal adult skin. HoxB6 protein also has nuclear expression in hyperproliferative skin conditions, but appears to be localized in the cytoplasm in basal and squamous cell carcinomas. HoxB6 genes are also expressed in normal adult lung. Function: HOXB6 belongs to the homeobox family. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Subcellular Location: Nuclear Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the Antp homeobox family. Contains 1 homeobox DNA-binding domain. SWISS: P17509 Gene ID: 3216 Database links: Entrez Gene: 3216 Human Entrez Gene: 15414 Mouse Entrez Gene: 497986 Rat Omim: 142961 Human SwissProt: P17509 Human SwissProt: P09023 Mouse Unigene: 98428 Human Unigene: 215 Mouse

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