Product Name	Calneuron 1
Chinese Name	钙营养蛋白1/钙Binding protein8抗体
Alias	CaBP8; CABP8_HUMAN; Calcium binding protein 8; Calcium binding protein; Calcium binding protein CABP8; Calcium-binding protein 8; Caln1; Calneuron I; Calneuron-1; Calneuron1.
Research Area	Cell biology  Neurobiology  Signal transduction  Binding protein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	25kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Calneuron 1/CABP8: 51-150/219
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]. Function: Negatively regulates Golgi-to-plasma membranetrafficking by interacting with PI4KB and inhibiting its activity(By similarity). May play a role in the physiology of neurons andis potentially important in memory and learning. Subunit: Interacts with PI4KB. This binding competes withFREQ/NCS1 binding in a calcium-dependent manner. Subcellular Location: Golgi apparatus, trans-Golgi network membrane. Cytoplasm, perinuclear region. Cell membrane. Tissue Specificity: Brain specific. Similarity: Contains 2 EF-hand domains. SWISS: Q9BXU9 Gene ID: 83698 Database links: Entrez Gene: 83698 Human Entrez Gene: 140904 Mouse Entrez Gene: 363909 Rat Omim: 607176 Human SwissProt: Q9BXU9 Human SwissProt: Q9JJG7 Mouse SwissProt: Q06BI3 Rat Unigene: 592750 Human Unigene: 320206 Mouse Unigene: 202895 Rat

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