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Product Name ANKRD5 Chinese Name 锚蛋白重复域5抗体 Alias ANKR5_HUMAN; ANKRD 5; ANKRD5; Ankyrin repeat domain 5; Ankyrin repeat domain containing protein 5; Ankyrin repeat domain-containing protein 5; dJ839B4.6; FLJ21669. Research Area Cell biology Neurobiology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Pig, Cow, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 87kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ANKRD5: 1-100/776 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail ANKRD5 is a 776 amino acid protein that contains one calcium-binding EF-hand domain and 8 ankyrin repeats. The gene encoding ANKRD5 maps to chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.
Similarity:
Contains 8 ANK repeats.
Contains 1 EF-hand domain.
SWISS:
Q6NXT1
Gene ID:
129138
Database links:Entrez Gene: 129138 Human
Entrez Gene: 223690 Mouse
Omim: 613383 Human
SwissProt: Q6NXT1 Human
SwissProt: Q91WK7 Mouse
Unigene: 135259 Human
Unigene: 24262 Mouse
Unigene: 28758 Rat
Product Picture Paraformaldehyde-fixed, paraffin embedded (rat pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ANKRD5) Polyclonal Antibody, Unconjugated (SL12158R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.Paraformaldehyde-fixed, paraffin embedded (rat stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ANKRD5) Polyclonal Antibody, Unconjugated (SL12158R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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