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Product Name DBX2 Chinese Name 脑发育同源蛋白2抗体 Alias Dbx 2; developing brain homeobox 2; FLJ16139; hlx3; DBX2_HUMAN. Research Area Cell biology Developmental biology Neurobiology Signal transduction Stem cells Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Human, Mouse, Rat, (predicted: Chicken, Dog, Pig, Horse, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 37kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human DBX2: 151-250/339 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail DBX2 is a 339 amino acid member of the H2.0 homeobox family. DBX2, which is localized to the nucleus, contains one homeobox DNA-binding domain, a region of 60 amino acids that binds DNA through a helix-turn-helix type of structure. DBX2, which is expressed in the forebrain, midbrain, hindbrain and spinal cord, has been implicated in CNS development.Specifically, DBX2 has been shown to play a role in spinal cord dorsal/ventral patterning, as well as the regionalization of the CNS. DBX2 is also thought to play a role in the production of multiple spinal cord cell types.
Subcellular Location:
Nuclear
Similarity:
Belongs to the H2.0 homeobox family.
Contains 1 homeobox DNA-binding domain.
SWISS:
Q6ZNG2
Gene ID:
440097
Database links:Entrez Gene: 440097 Human
Entrez Gene: 223843 Mouse
SwissProt: Q6ZNG2 Human
Unigene: 302764 Human
Unigene: 152937 Mouse
Unigene: 93216 Rat
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