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Product Name GABRG1 Chinese Name G氨基丁酸受体γ1/GABAA Rγ1抗体 Alias GABA A Receptor gamma 1; GABA(A) receptor subunit gamma 1; GabaA/BZ; GABRG 1; GABRG1; Gamma aminobutyric acid (GABA A) receptor subunit gamma 1; Gamma aminobutyric acid A receptor, gamma 1; GBRG1; Research Area Neurobiology The cell membrane受体 G protein-coupled receptor G protein signal Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 50kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GABRG1: 65-160/465 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene belongs to the ligand-gated ionic channel family. It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. This gene is clustered with three other family members on chromosome 4. [provided by RefSeq, Jul 2008]
Function:
GABA A Receptor gamma 1 belongs to the ligand gated ionic channel family. It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel.
Subunit:
Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.
Subcellular Location:
Cell junction, synapse, postsynaptic cell membrane; Multi pass membrane protein.
Post-translational modifications:
May be palmitoylated
Similarity:
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG1 sub-subfamily.
SWISS:
Q8N1C3
Gene ID:
2565
Database links:Entrez Gene: 2565 Human
Entrez Gene: 14405 Mouse
Omim: 137166 Human
SwissProt: Q8N1C3 Human
SwissProt: Q9R0Y8 Mouse
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