Product Name	GPR136
Chinese Name	G protein-coupled receptor136抗体
Alias	G protein-coupled receptor 136; G-protein coupled receptor PGR12; Gpr136; HGNC:21318; Neuropsin; OPN5; Opsin 5; PGR12; TMEM13; Transmembrane protein 13; OPN5_HUMAN; GPCR GPR136.
Research Area	Neurobiology  Signal transduction  The cell membrane受体  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	40kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human G protein-coupled receptor 136: 11-110/354 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	GPCR GPR136, also known as Opsin 5, is a member of the guanine nucleotide binding protein (G protein) coupled receptor superfamily. This gene belongs to the seven exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven exon opsin genes, this gene may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants encoding different isoforms. ESTs for the GPR136 gene have been identified from human normal testis and B cell/lung/testis libraries.. Subcellular Location: Membrane; Multipass membrane protein. Tissue Specificity: Detected in brain and retina and cell lines derived from neural retina. Post-translational modifications: It is uncertain whether Cys-315 or Cys-316 is palmitoylated. Similarity: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. SWISS: Q6U736 Gene ID: 221391 Database links: Entrez Gene: 221391 Human Entrez Gene: 353344 Mouse Entrez Gene: 316259 Rat SwissProt: Q6U736 Human SwissProt: Q6VZZ7 Mouse SwissProt: Q7TQN6 Rat Unigene: 213717 Human Unigene: 184937 Mouse Unigene: 97222 Rat

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