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Product Name Omgp Chinese Name 少突细胞髓磷脂glycoprotein抗体 Alias olyigodendrocyte myelin glycoprotein; OMG; OMGP; Oligodendrocyte-myelin glycoprotein; OMGP_HUMAN. literatures Specific References (1) | SL1200R has been referenced in 1 publications.[IF=1.27] Feng, Nianping, et al. "Transplantation of mesenchymal stem cells promotes the functional recovery of the central nervous system following cerebral ischemia by inhibiting myelin‑associated inhibitor expression and neural apoptosis." Experimental and Therapeutic Medicine. IHC-P ; Rat.Research Area Neurobiology Signal transduction Apoptosis Immunogen Species Rabbit Clonality Polyclonal React Species Human, Mouse, Rat, (predicted: Cow, ) Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 43kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Omgp: 166-280/440 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Oligodendrocyte myelin glycoprotein (OMG) is a glycosylphosphatidylinositol (GPI)-anchored CNS myelin protein, which is a potent inhibitor of neurite outgrowth in cultured neurons, and contributes significantly to the inhibitory activity associated with CNS myelin.
Function:
Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.
Subunit:
Binds to RTN4R.
Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Specificity:
Oligodendrocytes and myelin of the central nervous system.
Post-translational modifications:
O-glycosylated in its Ser/Thr-rich repeat domain (Potential).
Similarity:
Contains 8 LRR (leucine-rich) repeats.
Contains 1 LRRNT domain.
SWISS:
P23515
Gene ID:
4974
Database links:
Entrez Gene: 4974 Human
Entrez Gene: 100172122 Orangutan
Omim: 164345 Human
SwissProt: P23515 Human
Unigene: 113874 Human
OMgp也是髓鞘glycoprotein的一种,在发育期促进轴突生长,成熟期抑制轴突生长.其抑制作用主要由髓鞘来源的抑制分子的共同受体NgR介导,在神经营养因子受体p75NTR以及小GTP酶Rho等信号分子的共同参与下完成.Product Picture Sample: Medulla (Mouse) Lysate at 30 ug
Primary: Anti- Omgp (SL1200R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 43 kD
Observed band size: 49 kD
Sample:
Lane 1: Mouse Cerebrum tissue lysates
Lane 2: Mouse Cerebellum tissue lysates
Lane 3: Rat Cerebrum tissue lysates
Lane 4: Rat Cerebellum tissue lysates
Primary: Anti-Omgp (SL1200R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 43 kDa
Observed band size: 48 kDa
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