Product Name	NRSN1
Chinese Name	神经囊泡膜蛋白1抗体
Alias	Neurensin-1; Neuro-p24; NRSN1; NRSN1_HUMAN; p24; Vesicular membrane protein of 24 kDa; Vesicular membrane protein p24; VMP.
Research Area	Cell biology  Developmental biology  Neurobiology  Signal transduction  The cell membrane蛋白
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Horse, Rabbit, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	21kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human NRSN1: 101-195/195
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Neurensin-1 (NRSN1), also designated Vesicular membrane protein of 24 kDa (VMP) or Neuro-p24, is a 195 amino acid multi-pass membrane protein belonging to the VMP family that is involved in the transport of neural organelle transport and in the transduction of nerve signals or in nerve growth. Expressed solely in brain, Neurensin-1 is also thought to play a role in neurite extension. The gene encoding Neurensin-2 maps to human chromosome 6, which contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. Function: May play an important role in neural organelle transport, and in transduction of nerve signals or in nerve growth. May play a role in neurite extension. Subcellular Location: Membrane. Localizes mainly to neurites. Tissue Specificity: Expressed in brain. Not detectable in other tissues tested. Similarity: Belongs to the VMP family. SWISS: Q8IZ57 Gene ID: 140767 Database links: Entrez Gene: 140767 Human Entrez Gene: 22360 Mouse Entrez Gene: 291129 Rat SwissProt: Q8IZ57 Human SwissProt: P97799 Mouse Unigene: 726270 Human Unigene: 4766 Mouse Unigene: 225156 Rat

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