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Product Name ACBD3 Chinese Name 高尔基复合体相关蛋白1抗体 Alias GOCAP1; ACBD 3; ACBD3; Acyl CoA binding domain containing protein 3; Acyl Coenzyme A binding domain containing 3; Acyl-CoA-binding domain-containing protein 3; GCP 60; GCP60; GCP60_HUMAN; GOCAP 1; GOCAP1; Golgi complex associated protein 1 60kDa; Golgi complex associated protein 1; Golgi complex-associated protein 1; Golgi phosphoprotein 1; Golgi resident protein GCP60; GOLPH 1; GOLPH1; PAP 7; PAP7; PBR and PKA associated protein 7; PBR associated protein; PBR- and PKA-associated protein 7; Peripheral benzodiazepine receptor associated protein PAP7; Peripheral benzodiazepine receptor-associated protein PAP7; Peripherial benzodiazepine receptor associated protein; PKA (RIalpha) associated protein. Research Area Cell biology Signal transduction Growth factors and hormones Cyclin Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Rat, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 60kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ACBD3/GOCAP1: 65-160/528 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is involved in the maintenance of Golgi structure and function through its interaction with the integral membrane protein giantin. It may also be involved in the hormonal regulation of steroid formation. [provided by RefSeq, Jul 2008]
Function:
Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells.
Subunit:
Interacts with the C-terminal cytoplasmic domain of giantin/GOLGB1. Interacts with PBR and PKA regulatory subunit RI-alpha. Does not interact with PKA regulatory subunit RI-beta nor PKA regulatory subunit RII-alpha
Subcellular Location:
Golgi apparatus membrane. Mitochondrion. Also mitochondrial (via its interaction with PBR).
Tissue Specificity:
Ubiquitous, with highest expression in testis and ovary.
Similarity:
Contains 1 ACB (acyl-CoA-binding) domain.
Contains 1 GOLD domain.
SWISS:
Q9H3P7
Gene ID:
64746
Database links:Entrez Gene: 64746 Human
Entrez Gene: 170760 Mouse
Omim: 606809 Human
SwissProt: Q9H3P7 Human
SwissProt: Q8BMP6 Mouse
Unigene: 520207 Human
Unigene: 272981 Mouse
Unigene: 57036 Rat
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