Product Name	NME4
Chinese Name	Tumour转移抑制基因H4抗体
Alias	mitochondrial; NDK; NDKM_HUMAN; NDP kinase; NDP kinase, mitochondrial; NDPKD; nm23 H4; nm23-H4; NM23D; Nm23M4; NME4; Non metastatic cells 4 protein expressed in; Nucleoside diphosphate kinase D; Nucleoside diphosphate kinase, mitochondrial.
Research Area	Tumour  Cell biology  Signal transduction  transcriptional regulatory factor  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Pig, Cow, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	18kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human NME4/nm23-H4: 21-120/187
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The nucleoside diphosphate (NDP) kinases (EC 2.7.4.6) are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates. The enzymes are products of the nm23 gene family, which includes NME4 (Milon et al., 1997 [PubMed 9099850]).[supplied by OMIM, May 2008] Function: Major role in the synthesis of nucleoside triphosphates other than ATP. Subunit: Homohexamer. Interacts with CAPN8 Subcellular Location: Mitochondrion intermembrane space. Tissue Specificity: Widely distributed. Found at very high levels in prostate, heart, liver, small intestine, and skeletal muscle tissues, and in low amounts in the brain and in blood leukocytes. Similarity: Belongs to the NDK family. SWISS: O00746 Gene ID: 4833 Database links: Entrez Gene: 4833 Human Omim: 601818 Human SwissProt: O00746 Human Unigene: 9235 Human
Product Picture	Paraformaldehyde-fixed, paraffin embedded (mouse cerebellum); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NME4) Polyclonal Antibody, Unconjugated (SL11902R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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