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Product Name NT5C2 Chinese Name 胞浆-5´-核苷酸酶-Ⅱ抗体 Alias 5' nucleotidase (purine) cytosolic type B; 5NTC_HUMAN; cN II; Cytosolic 5''-nucleotidase II; Cytosolic IMP/GMP-specific 5'-nucleotidase; Cytosolic purine 5' nucleotidase; Cytosolic purine 5''-nucleotidase; GMP; NT5B; nt5c2; NT5CP; NUCLEOTIDASE, 5-PRIME, CYTOSOLIC II; NUCLEOTIDASE, 5-PRIME, TYPE B; PNT5; PURINE 5-PRIME-NUCLEOTIDASE; PNT5. literatures Specific References (1) | SL0372R has been referenced in 1 publications.[IF=0] Gstraunthaler, Gerhard, et al. "Human platelet lysates successfully replace fetal bovine serum in adipose-derived adult stem cell culture." Journal of Advanced Biotechnology and Bioengineering 2.1 (2014): 1-11. IF(ICC) ; Human.Research Area Cardiovascular Cell biology immunology Chromatin and nuclear signals Cell Surface Molecule Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 65kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NT5C2: 1-100/561 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides. [provided by RefSeq, Oct 2011]
Function:
May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.
Subunit:
Homotetramer.
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the 5'(3')-deoxyribonucleotidase family.
SWISS:
P49902
Gene ID:
22978
Database links:
Entrez Gene: 22978 Human
Entrez Gene: 76952 Mouse
Omim: 600417 Human
SwissProt: P49902 Human
SwissProt: Q3V1L4 Mouse
Unigene: 97439 Human
Unigene: 40965 Mouse
CD-73(胞浆-5´-核苷酸酶-Ⅱ)具有水解酶及磷酸转移酶的活性,在调解核苷酸的平衡中发挥着重要作用.
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