Product Name	human IgA
Chinese Name	羊抗人免疫球蛋白A
Alias	IgA1; Igh2; IGHA1; IGHA2; Immunoglobulin heavy constant alpha 1; Immunoglobulin heavy constant alpha 2 (A2m marker); Immunoglobulin heavy constant alpha 2; human Immunoglobulin A.
Immunogen Species	Goat
Clonality	Polyclonal
React Species	Human,
Applications	ELISA=1:2000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	170kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	Full length plasma protein: full length
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids and milk. Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces. The production is usually local and antigen specific IgA producing B-cells can be found in regions under the lamina propria where they mature into dimeric IgA producing plasma cells. IgA deficiency is the most common immunodeficiency that may affect both serum and mucosal produced IgA. Subcellular Location: Secreted. SWISS: P01876 Gene ID: 3493 Database links: Entrez Gene: 3493 Human Entrez Gene: 3494 Human Omim: 146900 Human Omim: 147000 Human SwissProt: P01876 Human SwissProt: P01877 Human

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