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Product Name CMTM2 Chinese Name 趋化素样因子超家族成员2抗体 Alias Chemokine like factor super family 2; Chemokine like factor superfamily 2; Chemokine like factor superfamily member 2; CKLF like MARVEL transmembrane domain containing; CKLF like MARVEL transmembrane domain containing protein 2; CKLFSF2; CMTM 2; CMTM2; CMTM-2; CKLF2_HUMAN. Research Area Tumour Cell biology immunology Developmental biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Human, Applications WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 27kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CKLFSF2: 23-100/248 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene belongs to the chemokine-like factor gene superfamily, a novel family that links the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. [provided by RefSeq, Jul 2008]
Subcellular Location:
Membrane; Multi-pass membrane protein.
Tissue Specificity:
Highly expressed in testis.
Similarity:
Belongs to the chemokine-like factor family.
Contains 1 MARVEL domain.
SWISS:
Q8TAZ6
Gene ID:
146225
Database links:
Entrez Gene: 146225 Human
Omim: 607885 Human
SwissProt: Q8TAZ6 Human
Unigene: 195685 Human
CKLFSF2蛋白特异性的表达于减数分裂及分裂后的各级生精细胞中,它定位于高尔基体周围的内质网上,而且和生精功能损害密切相关。
CKLFSF2可能在减数分裂及精子生成的过程中发挥重要作用,并可能与内质网的囊泡转运和膜定位过程相关联。
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